Neurotropic Parasite Toxoplasma gondii and Immunosuppressed Patients
نویسنده
چکیده
Toxoplasmosis is an anthropozoonosis caused by the protozoan Toxoplasma gondii, an obligate intracellular parasite belonging to the phylum Apicomplexa. It presents a cosmopolitan geographic distribution, with high rates of infection in humans; capable of infecting nucleated cells from a wide variety of hosts. Toxoplasmosis is one of the most common opportunistic infections affecting HIV positive patients; being the neurotoxoplasmosis, the most prevalent brain focal lesion in these patients. In addition, patients with low CD4+ T-cell counts are at high risk of developing life-threatening reactivated cerebral toxoplasmosis.
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